What is the action of gatifloxacin drops prescribed for an eye infection?

The action of gatifloxacin drops, which are part of the fluoroquinolone antibiotic class, primarily involves inhibiting DNA synthesis in susceptible bacteria. Gatifloxacin targets bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and transcription. By interfering with these enzymes, gatifloxacin effectively halts the ability of bacteria to replicate and repair their DNA, leading to bacterial cell death.

This mechanism is particularly effective against both gram-positive and some gram-negative bacteria, making gatifloxacin a suitable option for treating a variety of bacterial eye infections. Understanding this action helps in grasping how gatifloxacin functions as a potent antibacterial agent in the context of ophthalmic infections.